Skin cancer risk is higher for adults with atopic dermatitis
According to a study presented, adults with atopic dermatitis (AD) have an increased risk of developing melanoma, basal cell carcinoma (BCC), and squamous cell carcinoma (SCC), with a significantly higher risk for moderate-to-severe AD than mild. at the annual meeting of the American Academy of Dermatology, held March 17-21 in New Orleans.
Margaret Y. Huang, from the University of Southern California’s Keck School of Medicine in Los Angeles, and colleagues examined the risk of developing melanoma, SCC, and BCC in adults with AD in a cohort study. The retrospective system used a claims database for 2007 to 2021. Data were included for 60 million adults 18 years of age and older with and without a diagnosis of AD who later developed tumors. malignancy, SCC or BCC.
The researchers found that adults with AD had a significantly higher risk of developing melanoma, SCC, and BCC than those without AD (relative risk 1.23, respectively. 1.27 and 1.28) after adjusting for confounding variables. Adults with moderate to severe AD had a significantly higher risk of developing melanoma, SCC, and BCC than those with mild AD (relative risks 1.11, 1.25 and 1.17).
“In summary, our findings support an increased risk of developing melanoma, SCC and BCC in adult patient with AD regardless of AD severity,” the authors write. “More mechanistic studies are needed to understand AD and the development of skin cancer.”
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