New immunotherapeutic strategies in complex targeting in the tumor microenvironment

A symposium aimed at providing a better understanding of the tumor microenvironment, immune tolerance niches at cancer initiation, and novel immunotherapeutic strategies in patients with head and neck cancer. presented at this symposium. AADOCR . 52nd Annual Conference & Exhibition, held in conjunction with CADR’s 47th Annual Meeting. The AADOCR/CADR Annual Convention & Exhibition took place at the Oregon Convention Center in Portland on March 15-18, 2023.

Cancer immunotherapy has developed as a promising new treatment modality for head and neck cancer (HNC), building on the growing understanding of tumor immunity over the past two decades. via. However, it is clear that not all tumors are created equal when it comes to their immune profiles, and many tumors are resistant to immunotherapy. Therefore, a better understanding of the complex tumor microenvironment is needed to more accurately define prognosis and design. treatment strategy potentially sensitize tumors to immunotherapy and the immunological effects of conventional therapies.

Hosted by Simon Young of the University of Texas Health Science Center at Houston, this symposium provided a high-level overview of exciting developments in understanding the tumor microenvironment. , both in terms of the complex immunosuppressive mechanism of the extracellular matrix, the induction of an immune system. appropriate tolerance at cancer initiation and how novel immunotherapeutic strategies can adversely target the tumor immune microenvironment in head and neck cancer. Prominent scientist-clinician speakers present a wide range of expertise: topics include current challenges in HNC surgical resection strategies and immune tolerance niche formation translation at the onset of cancer. This is followed by novel strategies to target fibromyalgia and biomaterials-based strategies for cancer immunotherapy and providing treatments for immunosuppressed patients. tumor microenvironment.

Symposium targeted at dental students, graduate students, dentists, dentist-scientists and scientists who wish to expand their knowledge of the tumor immune microenvironment and how Cancer immunotherapy will affect the head and neck cancer patient. This section is aimed at clinicians and researchers.

Provided by the International Association for Dental Research