Finally, the researchers examined lac-phe in other exercised organisms. They first found it in the blood of racehorses in much higher concentrations after a harder run than before. They then asked eight healthy young adults to exercise three times: once by cycling at a leisurely pace for 90 minutes, another time lifting weights, and a third time sprinting for 30 seconds on a bike. stationary bike. Lac-phe blood levels peak after each type of exercise, but they are highest after sprinting, followed by weight training. Gentle stretching exercises cause the least effect.
In other words, the more intense the exercise, the more lac-phe was produced, and at least in the rats, the lower the appetite.
“The results are fascinating and add a new dimension to our thinking about exercise,” said Richard Palmiter, a professor of biochemistry at the University of Washington in Seattle and an expert in the neurobiology of behavior. fitness and body weight regulation. new research.
“We’ve always known that our current menu of molecules that can regulate appetite and food intake, such as leptin, ghrelin, etc., is incomplete and new signaling/metabolizing molecules. This is a potentially important addition to that list,” said Barry Braun, executive director of the Human Performance Clinical Research Laboratory at Colorado State University at Fort Collins, who studies collectives. exercise and weight control. He was not involved in the new study.
Assuming the process works similarly in humans as it does in mice, the discovery of lac-phe would provide a useful lesson. If we want to avoid getting drunk Jonathan Z. Long, professor of pathology at Stanford University School of Medicine and lead author of the new study, says that after a workout, we may need to increase the intensity of our exercise.
The idea has intuitive and evolutionary implications, he added. “If you’re sprinting from a rhinoceros or some other threat, the autonomic nervous system screams at the brain to stop digestion and any other unnecessary processes.”
