According to a study published online on December 29 in the journal JAMA Otolaryngology-Head & Neck Surgery.
Elise De Cuyper, MD, from Ghent University in Belgium, and colleagues conducted a cross-sectional study of infants infected with cCMV from six primary and tertiary hospitals over 15 years (from 1 May). 1 2007 to 7 February 2022) to identify independent risk factors for cCMV-associated congenital disease hearing loss.
The researchers found that 416 and 617 (40.3 and 59.7 percent) of the 1,033 Infant included in the study were diagnosed with symptomatic cCMV infection and asymptomatic cCMV infection, respectively. Overall, 15.4% of patients had congenital hearing loss, 50.3% of whom had isolated hearing loss. Three independent factors for congenital hearing loss were identified in a regression model: petechiae at birth, periventricular cysts. Magnetic Resonance imaging (MRI) and seroconversion in the first trimester (adjusted odds ratios, 6.7, 4.6, and 3.1, respectively). Patients with normal hearing had a lower viral load than patients with congenital hearing loss (mean viral load, 447.0 vs 1,349.5 copies/mL).
“Infants with cCMV infection with petechiae at birth, periventricular cysts on MRI, or seroconversion during the first trimester have a higher risk of congenital hearing loss,” the authors write. “These risk factors can be used by clinicians to advise parents in the pre- and postnatal period about the risk of congenital hearing loss.”
Elise De Cuyper et al., Risk factors for hearing loss at birth in neonates with congenital cytomegalovirus infection, JAMA Otolaryngology–Head & Neck Surgery (2022). DOI: 10.1001/jamaoto.2022.4109
Albert H. Park, Detection of Hearing Loss in Children with Congenital Cytomegalovirus—Finding a Needle in the Bottom of a Tank, JAMA Otolaryngology–Head & Neck Surgery (2022). DOI: 10.1001/jamaoto.2022.4155
Copyright © 2022 health day. Copyright Registered.
quote: Identified factors causing hearing loss in neonates with congenital cytomegalovirus (2022, 30 December) retrieved 30 December 2022 from https://medicalxpress.com/news/2022- 12-factors-loss-newborns-congenital-cytomegalovirus.html
This document is the subject for the collection of authors. Other than any fair dealing for private learning or research purposes, no part may be reproduced without written permission. The content provided is for informational purposes only.
