Karin Hammarberg, lead author of Monash University, Melbourne, Australia.
“Together with previous evidence that adults conceived with ART have similar physical health to those conceived naturally, this puts those conceived with ART – and those in need of ART for conception is reassuring.”
In the more than four decades since the first birth after in vitro fertilization (IVF) in 1978, more than 8 million children have been born on ART. During that time, numerous studies have evaluated the physical, developmental, and psychosocial health of children treated with ART compared with children conceived naturally (NC). But currently, little is known about the health and quality of life of adults conceived by in vitro fertilization (IVF). These participants completed a questionnaire, which included a standardized measure of quality of life (Quality of Life – World Health Organization Summary Assessment (WHOQoL-BREF)), at 18 -28 years old (T1) and again at 22-35 years old (T2) .
WHOQoL-BREF assesses four dimensions of quality of life: 1) physical 2) psychosocial 3) social relationships and 4) environment. In vitro fertilization (IVF)
The researchers examined the association between factors present at T1 (mode of conception, maternal age when participants were born, sexual orientation, family financial situation in middle school) school, self-weight perception, number of close friends, frequency of physical activity, and quality of relationship with parents) and WHOQoL-BREF four-area scores at T2.
After making statistical adjustments to account for other psychosocial factors present in adolescence, the results showed that being conceived with ART was strongly associated with higher scores (quality of life). live better) on both social and environmental relationships in the WHOQoL-BREF field at T2.
In addition, less psychological distress, more positive relationships with parents, better financial status, and awareness of appropriate weight in T1 were associated with higher scores on one or more of the domains. WHOQoL-BREF at T2.
“Children conceived through ART today are a significant part of the population – and it is important to continue to assess the long-term impact of ART on their physical health and well-being as they grow older. progression through adolescence to adulthood”. Hammarberg said.
“When taking into account other factors that emerge in adolescence, being conceived with ART appears to confer some quality of life advantage. Perhaps not surprisingly, we also found that, independent of on how the person was formed, had better relationships with parents, less psychological distress, and better family financial situation in adolescence contributed to the person’s quality of life mature better.”
This is the first study to explore the contributions of being formed with ART and psychosocial factors in adolescence to adult quality of life. While these findings are reassuring, they should be interpreted with caution because many of the participants in the first study did not participate in the follow-up study.