Health

Body phenotypes say a lot, but not everything, about a person’s health, according to a new study.


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Concordia researchers studying body phenotypes—observable traits like height, behavior, appearance, and many other metrics—found that regardless of how muscular they were, How, high fat mass in an individual is associated with poorer overall health.

The findings, published in the journal Preventive health careused data from the US longitudinal study. They show that the negative effects of excess adipose tissue – adipose tissue – on a person’s cardiovascular metabolic health are not offset even when high levels of muscle mass.

The researchers based their study on data from the NHANES, a representative cross-sectional sample of the US population collected between 1999 and 2006. The data were collected using energetic X-ray absorometry. dual (DEXA), a diagnostic framework for fat analysis and muscle mass. Based on which side of the 50th percentile they ranked, individuals were classified into one of four suggested phenotypes: low fat/high muscle, high fat/high muscle, low fat/high muscle, or low fat /low -muscular.

The researchers looked at how fat/muscle phenotypes were related to lipid levels, including cholesterol and triglycerides, as well as blood sugar and blood pressure. Results were also adjusted for age, sex, race, and education.

“We wanted to see if this proposed classification was better than the traditional body mass index (BMI) in predicting all of these different cardiovascular metabolic outcomes,” said Sylvia Santosa, associate professor Professor in the Department of Health, Kinesiology and Applied Physiology and one of the people said. the authors of the article.

Surprisingly, they found that BMI, while imperfect, was in some cases a better predictor of cardiovascular metabolic risks such as diabetes and hypertension.

Associate Professor Lisa Kakinami, Concordia alumnus and current Rhodes Scholar Sabine Plummer, BSc 22, Ph.D. Students Jessica Murphy and Tamara Cohen of the University of British Columbia are co-authors of the paper.

Benefits of BMI

However, the data revealed some striking findings. Compared with the low fat/high muscle group, the healthiest of the four, the researchers noted the following results:

  • The two obese groups were less likely to be physically active and more likely to have abnormal lipids and a less healthy diet.
  • The high-fat/low-muscle group had higher total cholesterol, lower levels of high-density lipoprotein (“good” cholesterol), and lower nutrient intakes. This group was also 56 to 66% less likely to meet the weekly physical activity recommendations.
  • The high fat/high muscle group had unfavorable values ​​for all measures of heart and fat metabolism. Nutrient intake is also lower. This group was also 49 to 67 percent less likely to meet the physical activity recommendations, about 80 percent more likely to have high blood pressure, and more likely to exceed the recommended saturated fat intake. from 23 to 35%. Overall, the high-fat/high-muscle phenotype was the least likely to meet nutritional and physical activity recommendations, and had the highest risk of poor cardiometabolic health.
  • The low fat/low muscle group had significantly lower BMI and waist circumference. This group also had the lowest grip of the four phenotypes.

“If we are looking at cardiometabolic risk in population levelBMI can give you a cheap and quick idea of ​​what’s going on,” says Santosa.

More information:
Lisa Kakinami et al., Body composition phenotypes and their associations with cardiovascular metabolic risks and health behaviors in a representative US general sample, Preventive health care (2022). DOI: 10.1016/j.ypmed.2022.1078282

quote: Body phenotypes say a lot, but not everything, about a person’s health, according to new research (2023, January 25) obtained January 25, 2023 from https: //medicalxpress.com/news/2023-01-body-phenotypes-lot -person-health.html

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